Clinical Research | Pharmacokinetic Department

START Patient Care

The PK Department processes and ships all samples for the clinical trials conducted at START. Simple processing of the samples includes centrifugation followed by the transfer of plasma or serum and then freezing. Complex processing, such as harvesting peripheral blood mononuclear cells using specialized tubes, washes, lysis / fixation buffers, and storage media, is also routinely performed.

The PK laboratory manager, Brianne Kaiser, is an ASCP certified Medical Technologist. Laboratory personnel consists of six PK Technicians that are IATA certified via the SAF T Pak training course, and are very familiar with the requirements of the 49CFR and DGR in regards to handling and shipping hazardous materials.

The laboratory has up to date equipment to include four swing bucket centrifuges that can spin up to 3,000 g as well as a micro centrifuge that can spin up to 16,000 g. The centrifuges have room temperature capabilities as well as cold temperature capabilities (0-4°C). Yearly maintenance and calibrations are conducted on the equipment in order to maintain accurate speeds and temperatures. The lab is also equipped with two freezers (one -80°C and one -20°C) and a refrigerator / freezer. The -80°C and -20°C freezers are monitored continuously by an automated alert system that alerts the PK Department Manager or IDS Director if the temperature is close to being out of range.

The PK Department processes samples Mondays-Fridays from 8 am to 12 midnight, and a member from the department is available on Saturdays and Sundays from 8 am to 10 am to process samples that fall on the weekends. Shipment of the samples is also coordinated through the PK Department, which can accommodate daily, weekly, or monthly shipments.


Brianne Kaiser

Brianne Kaiser, MBA, MLS (ASCP)CM
PK Department and Tumor Bank Manager
START 4383 Medical Drive, Suite 3044
San Antonio, TX  78229
Phone:  (210) 593-5276
Fax:  (210) 593-5739